This directory contain scripts to parameterize rosetta using sequence profile data, the result is a soft core potential.

Usage: 
0. crack rosetta and set ddG weight to OPTE weight set
1. run a psi-blast for a set of proteins and get a series of multiple sequence alignment with the psi-blast
2. run the script to put the natural amino acid probability and all the energy term into a single file 
3. run make to get rosetta_profile_param
4. 

