RandomMutation.hh

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// -*- mode:c++;tab-width:2;indent-tabs-mode:t;show-trailing-whitespace:t;rm-trailing-spaces:t -*-
// vi: set ts=2 noet:
//
// (c) Copyright Rosetta Commons Member Institutions.
// (c) This file is part of the Rosetta software suite and is made available under license.
// (c) The Rosetta software is developed by the contributing members of the Rosetta Commons.
// (c) For more information, see http://www.rosettacommons.org. Questions about this can be
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/// @file protocols/protein_interface_design/movers/RandomMutation.hh
/// @author Sarel Fleishman (sarelf@u.washington.edu)

#ifndef INCLUDED_protocols_protein_interface_design_movers_RandomMutation_hh
#define INCLUDED_protocols_protein_interface_design_movers_RandomMutation_hh
#include <protocols/protein_interface_design/movers/RandomMutation.fwd.hh>
#include <core/types.hh>
#include <core/pose/Pose.fwd.hh>
#include <utility/tag/Tag.fwd.hh>
#include <protocols/filters/Filter.fwd.hh>
#include <protocols/moves/Mover.hh>
#include <core/pack/task/TaskFactory.fwd.hh>
#include <core/pack/task/PackerTask.fwd.hh>
#include <protocols/moves/DataMap.fwd.hh>
#include <core/scoring/ScoreFunction.fwd.hh>

#include <utility/vector1.hh>


namespace protocols {
namespace protein_interface_design {
namespace movers {

/// @brief designs alanine residues in place of the residue identities at the interface. Retains interface glycines and prolines.
class RandomMutation : public protocols::moves::Mover
{
public:
  typedef core::pose::Pose Pose;
public:
  RandomMutation();
  void apply( Pose & pose );
  virtual std::string get_name() const;
  protocols::moves::MoverOP clone() const;
  protocols::moves::MoverOP fresh_instance() const { return protocols::moves::MoverOP( new RandomMutation ); }
    void parse_my_tag( utility::tag::TagPtr const tag, protocols::moves::DataMap &, protocols::filters::Filters_map const &, protocols::moves::Movers_map const &, core::pose::Pose const & );
  virtual ~RandomMutation();
  core::pack::task::TaskFactoryOP task_factory() const;
  void task_factory( core::pack::task::TaskFactoryOP tf );
  core::scoring::ScoreFunctionOP scorefxn() const;
  void scorefxn( core::scoring::ScoreFunctionOP sfxn );
  bool cache_task() const;
  void cache_task( bool cache );
private:
  core::pack::task::TaskFactoryOP task_factory_;
  core::scoring::ScoreFunctionOP scorefxn_;
  bool cache_task_;
  core::pack::task::PackerTaskCOP task_;
};


} // movers
} // protein_interface_design
} // protocols


#endif /*INCLUDED_protocols_protein_interface_design_movers_RandomMutation_HH*/