scores a fragment by secondary structure similarity The score for each position is P(H), P(L) or P(E) if a vall residue is within Helix, Loop or Extended secondary stucture element, respectively. P(H), P(L) and P(E) denotes the probability that a given residue in a query is within Helix, Loop or Extended secondary stucture element. The total score of a fragment is a simple sum of all positions; for N-mer fragment is a sum of N terms
If P(H), P(L) and P(E) probabilities takes only 1.0 and 0.0 values, result of this scoring function should be the same as SecondaryIdentity, although the later one is faster. More...

#include <TalosSSSimilarity.hh>

Inheritance diagram for protocols::frag_picker::scores::TalosSSSimilarity:

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Collaboration diagram for protocols::frag_picker::scores::TalosSSSimilarity:

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Public Member Functions
	TalosSSSimilarity (Size priority, Real lowest_acceptable_value, bool use_lowest, core::fragment::SecondaryStructureOP query_prediction, std::string prediction_name, Size sequence_length, utility::vector1< Size > &frag_sizes, Size longest_vall_chunk)

	~TalosSSSimilarity ()

void	do_caching (VallChunkOP)

void	do_caching_simple (VallChunkOP)

bool	cached_score (FragmentCandidateOP f, FragmentScoreMapOP empty_map)

void	clean_up ()

virtual bool	score (FragmentCandidateOP, FragmentScoreMapOP)
	Computes the score. More...

core::fragment::SecondaryStructureOP	get_secondary_prediction ()
	returns the secondary structure porediction object that is used by this score More...

std::string &	get_prediction_name ()

Public Member Functions inherited from protocols::frag_picker::scores::CachingScoringMethod
	CachingScoringMethod (Size priority, Real lowest_acceptable_value, bool use_lowest, std::string name)

Public Member Functions inherited from protocols::frag_picker::scores::FragmentScoringMethod
	FragmentScoringMethod (Size priority, Real lowest_acceptable_value, bool use_lowest, std::string name)

std::string &	get_score_name ()
	Returns a name of this scoring method. More...

Size	get_id ()
	Returns an integer index assigned to this scoring method by a scoring manager. More...

void	set_id (Size id)
	Sets a new integer index for this scoring method. More...

Size	get_priority ()
	Returns a priority of this scoring method. More...

Real	get_min_allowed_score ()
	Returns the lowest acceptable score value for this scoring method. More...

bool	get_use_lowest ()
	Returns the boolean choice on using the above lowest acceptable score value. More...

void	set_min_allowed_score (Real lowest_acceptable_value)
	Sets a new value of the lowest acceptable score. More...

Protected Attributes
Matrix	scores_

utility::vector1< Matrix >	cache_

Private Attributes
std::string	prediction_name_

core::fragment::SecondaryStructureOP	query_ss_

utility::vector1 < utility::vector1< Real > >	raw_probs_

Size	query_len_

Real	H_mult_

Real	L_mult_

Real	E_mult_

std::string	cached_scores_id_

Detailed Description

scores a fragment by secondary structure similarity The score for each position is P(H), P(L) or P(E) if a vall residue is within Helix, Loop or Extended secondary stucture element, respectively. P(H), P(L) and P(E) denotes the probability that a given residue in a query is within Helix, Loop or Extended secondary stucture element. The total score of a fragment is a simple sum of all positions; for N-mer fragment is a sum of N terms
If P(H), P(L) and P(E) probabilities takes only 1.0 and 0.0 values, result of this scoring function should be the same as SecondaryIdentity, although the later one is faster.

Definition at line 44 of file TalosSSSimilarity.hh.

Constructor & Destructor Documentation

protocols::frag_picker::scores::TalosSSSimilarity::TalosSSSimilarity	(	Size	priority,
		Real	lowest_acceptable_value,
		bool	use_lowest,
		core::fragment::SecondaryStructureOP	query_prediction,
		std::string	prediction_name,
		Size	sequence_length,
		utility::vector1< Size > &	frag_sizes,
		Size	longest_vall_chunk
	)